Intelligent Living

Drug trial: No trace of disease left for terminally ill cancer patient

A patient with lung cancer who was given 12-18 months to live has no trace of the disease left after taking part in a drug trial at The Christie in Manchester, UK.

The patient, Bob Berry, was referred to the clinic after not responding to his standard treatment. His cancer spread from his lungs to his lymph nodes. Bob is one of the first patients in the UK to receive this treatment and The Christie is one of only six places in the World offering it. The treatment combines a drug with immunotherapy treatment in order to help make the drug more effective.

Bob Berry and Dr Matthew Krebs
Bob, pictured with Dr. Matthew Krebs, at The Christie

“As of his last scan, we’re not able to detect any lung cancer at all,” said Prof Hughes, chair in experimental cancer medicine at The Christie.

“The first drug damages the very essence of the cancer’s life – its DNA – and as the cancer is dying we hit it with a second drug that takes the ‘invisibility cloak’ away from the cancer so that the immune system can recognise it,” he added.

It is the first time this new drug has been tested in humans. Only 12 people have taken part in the trial globally.

“Every cancer drug begins with a ‘Bob’ story,” said Prof Hughes, “and then a larger trial is done”. It typically takes “three to seven years” to bring successful “first in human” trials into widespread use, he added.

Photo of Bob Berry's lungs, before on the right, after on the left, showing the missing white spot of cancer
Before (right) and after (left) scans of Bob’s lung show the cancer (the raised white dot) has been eradicated

Dr. Matthew Krebs, Bob’s consultant, stated that he still needs to undergo close monitoring to establish how successful the treatment may be in the long term and that much research still needs to be done as this treatment may not be as successful in different patients.

Bob states “three years ago, I was given 12-18 months to live but I have already surpassed that and I feel well. At the end of the day, this clinical trial at The Christie has extended my life and I couldn’t be more grateful. Anyone who is offered a clinical trial should seriously consider it.”

The other two patients in the hospital’s trial have responded to the treatment, but not to the degree Bob has.

The Christie is part of the UK National Health Service and are leading experts in cancer care, research, and education. It has been ranked as ‘Outstanding’ by the Care Quality Commission.

Related Articles

Mice implanted with human brain cells are more intelligent

Aaron Jackson

The World Health Organization Lists Vaccine Refusal As One Of The Top Ten Greatest Threats To World Health

Andrea D. Steffen

Molecule Making 3D Printer Can Create Billions Of Combinations

Aaron Jackson

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More